Translational Medicine Expert – Dermatology, Associate Director

As a Translational Medicine Expert (TME) based in Basel, Switzerland, you will provide medical and scientific expertise and leadership to drive the success of early and late global programs in dermatology, develop and implement strategies to achieve Transition Decision Point (TDP), and support translational research in developing new indications, endpoints, and biomarkers.

• Develop and implement strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications, including post-indication expansion (PIE) projects, in collaboration with the dermatology TA and teams.
• Act as a key leader in developing Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) with other TM line functions.
• Provide support for dose selection, study design, and other clinical pharmacology matters throughout the development cycle.
• Oversee conduct and interpretation of studies prioritized to support pivotal trials, such as special populations, drug-drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc.
• Develop strategies to identify initial or expansion (PIE) indications and obtain sufficient evidence to fund these ideas, in collaboration with the dermatology TA Head, BR Research scientists, and other TM line functions.
• Participate on Business Development and Licensing (BD&L) teams as the TM representative for in-licensing and out-licensing compounds.
• Responsible for clinical monitoring and integrated safety data review during and after the live phase of a study.
• Provide medical and scientific leadership and expertise to all line functions on the study team.
• Represent clinical Translational Medicine aspects to Health Authorities and other stakeholders such as payers and patient advocacy groups.
• Oversee publication strategy for TM studies, lead writing of scientific publications, and present study results externally where appropriate.
• Lead study-specific teams and clinical trial teams in partnership with other line functions.
• Lead BR-sub-teams on Global Project Teams for late-phase programs.
• Collaborate closely with other TM and non-TM line functions to ensure operational excellence, urgency, and attention to timelines, costs, and subject burden, while maintaining high scientific standards and innovation.