For the prestigious PhD School of the Swiss Nanoscience Institute (SNI), applications are invited for a paid 4-year PhD student position jointly supervised by Prof. Sonja Schmid (biophysical chemistry) and Prof. Florian P. Seebeck (bioinorganic chemistry). The project focuses on developing cutting-edge protein nanopore technology for single-molecule analysis of metal nanoclusters, aiming to provide new insights into the functional roles of heterogeneity in prebiotic life and novel materials.
Tasks
- Work on the development of a nanopore-based platform for single-molecule analysis of nanoclusters.
- Establish nanopore assays for detecting and characterizing individual nanoclusters.
- Engineer and purify protein nanopores with tailored sensitivity to size, charge, and other properties.
- Develop data analysis pipelines and machine learning approaches for signal classification.
- Collaborate within an interdisciplinary team of physicists, chemists, and molecular life scientists.
- Present findings at conferences and in scientific publications.
Requirements
- Master's degree (or equivalent) in chemistry, biochemistry, nanoscience, physics, or a related field.
- Previous knowledge about nanopore experiments, protein purification, and/or machine learning is a clear plus.
- Experience in data analysis and coding (preferably Python).
- Systematic, independent working style and ability to work in a collaborative environment.
- Excellent communication skills in English in speaking and writing.
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Über uns
Das Team
The position is jointly supervised by experts in biophysical and bioinorganic chemistry and involves collaboration within an interdisciplinary team of physicists, chemists, and molecular life scientists.